Skip to main content

Diane Brzezinski, D.O. FACOI

Call for an appointment | 239.261.9990

Dr. B's Blog

ProLon Weight Loss®

ProLon®’s Health and Medical Weight Loss Benefits

If you are one of the millions of Florida residents who struggle to control their weight, it might be time to think about fasting. And, no, we’re not talking about starve-yourself fasting, in which you only consume water for a specified number of days. We’re steering you towards a revolutionary dietary program that fools your body into going into a fasting state to provide you with similar weight loss and health benefits that can be gained by fasting.


So was Naples-based internal medicine specialist Dr. Diane Brzezinski, D.O., who successfully tried the diet herself before incorporating it as a component of her practice’s medical weight loss program. With numerous health benefits and the ability to help patients lose up to seven pounds of primarily abdominal fat with one three-month session, Dr. B says ProLon® is a rare success story in the diet industry.


ProLon®’s “5-Day Fasting Mimicking Diet” relies on a once-monthly five-day meal plan that tricks the body into entering a fasting state. Fasting can provide numerous health benefits, including weight loss, but many people struggle with the idea of abstaining from food. ProLon® lets people eat, but the body doesn’t recognize the meal plans’ nutritious ingredients as food.

Thus, dieters under the program get the benefits of fasting combined with the absorption of healthy nutrients, and they don’t have to struggle as much with hunger pangs. According to studies, once-monthly five days of ProLon® “fasting” confer many of the same benefits as a heart-healthy diet when practiced over several months.

Backed by more than 20 years of research and clinical trials, a three-month session of ProLon®, on average, helps patients lose seven pounds of fat and reduce body mass index (BMI) by about 4%. This can reduce up to 1.6 inches off one’s waist circumference by up to 1.6 inches and significantly boost metabolic and cardiovascular health.


ProLon® was developed at the University of Southern California’s Longevity Institute based on its research into autophagy, the body’s process for replacing damaged cells with new healthy ones. Because fasting significantly encourages autophagy, researchers focused on finding macronutrients that would not trigger the body’s cellular-level nutrient sensors. Composed of plant-derived proteins, carbohydrates, and healthy fats, ProLon®’s macronutrients nourish the body, but trick it into the autophagy-boosting fasting state.

While researchers were primarily interested in the health benefits of the fast-mimicking diet, fasting also puts the body into the metabolic ketosis state, which makes it turn to body fat as its primary fuel source. This added another health benefit to the ones derived from ProLon®’s autophagy-inducing ones. To date, ProLon® has undergone 21 human clinical trials and has been granted more than 40 patents worldwide for providing health benefits.


ProLon®’s magic begins on day one of the five-day session when your body’s metabolism starts transitioning into a fasting state. By day two, the fat-burning power of ketosis kicks into gear, and the cellular regeneration of autophagy ramps up on day three. Ketosis and autophagy continue on days four and five, with the latter sustaining for additional days. Depending on dietary choices following the five days of ProLon®, ketosis can be sustained, too.


Abdominal fat loss is the primary health benefit patients seek when they go on the ProLon® diet, but they reap plenty of other health benefits, too. These health benefits include:

  • Decreased blood pressure
  • Cellular rejuvenation
  • Enhanced metabolic function
  • Decreased triglyceride and cholesterol levels
  • Improved blood sugar levels
  • Reductions in inflammation
  • Healthier looking skin
  • Preservation of lean muscle mass during the diet

Many of ProLon®’s health benefits are noticeable after one session but are most apparent in patients who’ve repeated the diet in three consecutive months.


Anyone wanting to lose weight and boost their metabolic health is a good candidate for ProLon®. Even healthy adults in their normal weight range can benefit from ProLon®, though the company recommends that they only go on the diet once every three to six months. ProLon® is not recommended for pregnant or nursing women, anyone underweight, and those on medications to treat diabetes, heart disease, liver disease, kidney disease, or advanced cancer.


Dr. B would be happy to discuss the health benefits of ProLon® with you in a personal consultation. To schedule your ProLon® appointment or to learn more about Dr. B’s other holistic health services, contact her Naples-based Internal Medicine practice at (239) 261-9990.