Diane Brzezinski, D.O. FACOI

Call for an appointment | 239.261.9990

Medical Weight Loss

Medical weight loss naples fl

Dr. B – Trusted Weight Loss Doctors in Naples

Dr. Brzezinski, is one of the most highly experienced and trusted medical weight loss doctors in Naples, FL. Her internal medicine practice offers several effective weight loss programs including the Prolon Weight Loss which simulates prolonged fasting, and weight loss medication.

“Today, with obesity at epidemic proportions, everyone is thinking about weight loss and nutrition. As a board certified physician with a large internal medicine practice as well as a weight loss program, I have this conversation many times a day.”

Let’s face it, we all know how to eat. It just seems as if we need a push in the right direction. Our physician-supervised program is designed to do just that, and it can help you lose significant weight every month.

Using this multi-faceted approach including accountability, meal replacement, and in some cases weight loss medication, Dr. B can get you on the path to your ideal weight quickly and effectively.

Jump to…

Introducing The Prolon
Weight Loss Program

Prolon medical weight loss medication alternative

A diet program that mimics fasting for five days of each month, ProLon Weight Loss Professional has been clinically proven to enhance overall health while shedding abdominal fat. Dr. Brzezinski now offers this exciting new dietary program to her Naples, Florida-area internal medicine patients.

Unbelievable Results

ProLon’s® health and medical weight loss benefits are supported by more than 20 years of meticulous research and stellar results achieved in both pre-clinical and clinical trials, making it highly trusted by weight loss doctors. In addition to firmly boosting cardiovascular and metabolic health, a three-month session of ProLon® Professional produced on average:

  • 7 pounds of weight loss, primarily of abdominal fat
  • 4% reduction in body mass index (BMI)
  • Waist circumference reduction of 1.6 inches
  • 6% reduction of abdominal fat in those with BMIs greater than 25
  • Preservation of lean body mass
medical weight loss patient


ProLon® Professional is a dietary program designed to generate the weight loss and health benefits of water-only fasting while still allowing your body to absorb healthy nutrients. ProLon’s® Fasting Mimicking Diet® utilizes a five-day meal program with precisely measured micro and macronutrients. Your body will not recognize these scientifically researched nutrients as food, which will allow it to go into a fasting state.
prolon weight loss patients

Fasting has been practiced by numerous cultures and religions throughout history, but its potential health-boosting benefits are only now becoming understood. In recent years, researchers have identified numerous health benefits from fasting, including:

  • Lowered blood pressure
  • Decreased triglyceride and cholesterol levels
  • Boost in human growth hormone levels
  • Improved blood sugar levels
  • Decreased inflammation
  • Enhanced metabolic function
  • Improved cognitive function
  • Cellular rejuvenation
  • Weight loss

Fasting is not easy. ProLon’s® plant-based nutritional meals help surmount the difficulties of fasting while delivering healthy nourishment. Meanwhile, your bodily systems have been “tricked” into a fasting state, which provides its own unique health benefits. In fact, research shows that a five-day per month session of ProLon Weight Loss Professional can provide many of the same benefits as a daily, heart-healthy diet when conducted on at least three consecutive monthly cycles. 


Researchers at the Longevity Institute at the University of Southern California have been studying the nutritional theories underlying ProLon’s® effectiveness and safety for more than two decades before offering their system to weight loss doctors. Supported by almost $50 million in grant funding, the research has proven the ProLon® Professional program safe with more than 220,000 user experiences. Research also proved the effectiveness of ProLon® in helping users lose weight and boost overall health. One clinical study further demonstrated that the majority of health benefits were maintained for three months after completion of a three month ProLon® cycle. ProLon® has currently been issued five patents out of 19 filed to cover a variety of wellness benefits.


ProLon® Professional is designed to work easily into your day-to-day life. For a designated five days of each month, you have to commit yourself to eating only the Prolon® meals. This is less disruptive to the day-to-day routine than fasting, as the meals help stave off hunger. ProLon Weight Loss meals are individually packaged for each day and include plant-based energy bars, soups, assorted snacks, drinks, and supplements. These foods will not be recognized as such by your body, allowing it to go into a fasting state. Meanwhile, the foods themselves are optimized to provide nourishment, cellular rejuvenation, and healthy levels of metabolic markers.      

medical weight loss patient exercising


Dr. B joins more than 12,000 other medical weight loss doctors in 13 countries who now offer ProLon® Professional to their patients. With its numerous health benefits, Dr. B believes ProLon® Professional fits in well with her holistic-driven approach to treat the whole patient rather than specific conditions. Dr. B is excited about offering this new dietary program to her Naples, Florida-area patients and would be glad to discuss how ProLon® Professional might help you. To learn more about ProLon® Professional with Dr. B’s internal medicine practice contact her today at (239) 261-9990.

Weight Loss Peptides

In recent years medical researchers have uncovered the significant role peptides serve in maintaining cellular function and regulating autoimmune responses. Similar to proteins but with smaller amino acid chains, our body naturally produces thousands of different peptides, many of which play critical roles in maintaining good health. As we age, though, our natural peptide production declines, which can diminish proper bodily functioning. Peptide supplements and therapies can help restore youthful peptide levels, which can help improve metabolism, promote faster cellular healing, and offer other health benefits, including enhanced weight management.

In unlocking the secrets of peptides, researchers have discovered that some play a significant role in metabolism, fat storage, insulin production, inflammation, and other factors that affect weight gains and losses. Dr. B closely follows peptide research developments and is pleased to offer her Naples, Florida-area patients peptide therapies that have shown clinical promise in helping patients lose and manage weight.


Type 2 Diabetes Treatment and Long-Term Weight Management

Semaglutide is a glucagon-like peptide 1 receptor agonist that helps lower blood sugar levels by increasing insulin production. Semaglutide works by stimulating the growth of pancreatic beta cells, which help synthesize and secrete insulin and inhibit the production of glucagon, a hormone that increases blood sugar. The peptide also helps reduce body fat by slowing digestion and suppressing one’s appetite. Initially approved by the FDA for type 2 diabetes in injectable form in 2017 and as an oral medication in 2019, the FDA expanded its approval as an adjunct to diet and exercise for long-term weight management in 2021.

Semaglutide is prescribed for chronic weight loss to patients with a body mass index of 30 or greater (clinically obese) and to anyone considered overweight who has a weight-related condition, such as type 2 diabetes, high blood pressure or high cholesterol. In a 68-week double-blind trial of nearly 2,000 obese adults without type 2 diabetes, half in the Semaglutide group lost at least 15% of their body weight, while almost a third lost 20% (those in the placebo growth lost less than 2.4%).

PEA Advanced + Collagen Complex II

PEA Advanced + Collagen Complex II contains a high-quality source of palmitoylethanolamide that aims to support joint inflammation and pain, along with many other benefits. It includes two clinically-studied ingredients that offer superior absorption and performance, Levagen+ and KollaGen II-xs.


Amlexanox has powerful anti-inflammatory properties that can help disrupt the strong cyclical link between chronic inflammation and weight gain. While researchers continue to study this link, clinical evidence shows that chronic inflammation and the body’s hormonal and metabolic response feed off each other in a vicious circle to produce increases in both inflammation and weight gains. Traditionally used to treat ulcers, Amlexanox can help break this cycle first by helping to reduce inflammation by inhibiting the body’s release of histamines and leukotrienes. But Amlexanox goes further by also regulating other enzymes in a manner that boosts glucose metabolism and improves overall energy. Additionally, researchers believe that the peptide can also turn off the expression of fat genes, which can further help patients lose weight. Overall, Amlexanox benefits identified in clinical trials include:
  • Reductions in body fat
  • Improved insulin resistance
  • Improved glucose control
  • Improvements in hemoglobin levels

Weight-loss doctors often combine Amlexanox with Tetradecylthioacetic Acid (TTA) to optimize potential weight-loss results.


Designed to support the body’s natural fat-burning abilities, Thermo-Suppress is a non-stimulant/caffeine-free supplement containing two clinically-studied proprietary ingredients with GRAS status paired with two widely-studied compounds that target several key areas of weight management.


A peptide with 29 amino acids, Sermorelin optimizes growth hormone levels in adults. It does this by acting as a growth hormone secretagogue – which means it promotes the body’s natural growth hormone production without many of the risks associated with taking growth hormone directly. By replacing natural occurring deficiencies, sermorelin improves hormonal balance, enhances energy, burns fat, increases lean muscle mass, improves sleep quality, enhances memory, and improves the sex drive. When combined with proper diet and exercise, the results can be dramatic within three months. Sermorelin’s ability to reduce daytime fatigue combined with its weight loss properties make it useful in treating patients with diabetes as well. Research also suggests that the peptide provides anti-aging benefits by enhancing the immune system and protecting natural DNA sequences.
Glycine is an amino acid and neurotransmitter that has been successfully used to treat prostate gland enlargement, insomnia, schizophrenia, and stroke. It is used in combination with Sermorelin to optimize growth hormone production. The two are taken together by subcutaneous injection five out of seven nights during a week, 90 minutes after the last caloric intake.

Dr. B uses Sermorelin injections in conjunction with Amlexanox for a highly effective Triple-Play Weight Loss Program. Call our office at 239-261-9990 to find out if this program can help you achieve your weight loss goals.

plans for medical weight loss medication and diet

If you are interested in medical weight loss in Naples, FL, or to see if weight loss medication is right for you, please call our office today at 239-261-9990 (ask for Camille at ext 102). We have a special rate for new patients to help you get started today.

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Fit2Me is a FREE Type 2 Diabetes Program that’s custom fit for you.

With activities and recipes chosen just for you, we provide you the tools to build meals and activity plans, including ways to trade off excess calories with additional activity. Fit2Me can also be used to choose fun activities that work with your schedule, keep track of doctor visits, and explore treatment information.
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Fit2Me has 4 areas: My Food, My Activity, My Treatment Support, and My Plan Team.


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